2018 NBCF Endowed Chair Program

Image-based multiplex immune profiling of cancer tissues: translational implications. A report of the International Immuno-oncology Biomarker Working Group on Breast Cancer

CA Jahangir, DB Page, G Broeckx, CA Gonzalez, C Burke, C Murphy, JS Reis-Filho, A Ly, PW Harms, RR Gupta, M Vieth, AI Hida, M Kahila, Z Kos, PJ van Diest, S Verbandt, J Thagaard, R Khiroya, K Abduljabbar, G Acosta Haab

2024-03-01

Recent advances in the field of immuno-oncology have brought transformative changes in the management of cancer patients. The immu..

Pitfalls in machine learning-based assessment of tumor-infiltrating lymphocytes in breast cancer: a report of the international immuno-oncology biomarker working group

J Thagaard, G Broeckx, DB Page, CA Jahangir, S Verbandt, Z Kos, R Gupta, R Khiroya, K Abduljabbar, G Acosta Haab, B Acs, G Akturk, JS Almeida, I Alvarado-Cabrero, M Amgad, F Azmoudeh-Ardalan, S Badve, NB Baharun, E Balslev, ER Bellolio

2023-08-01

The clinical significance of the tumor-immune interaction in breast cancer is now established, and tumor-infiltrating lymphocytes ..

Spatial analyses of immune cell infiltration in cancer: current methods and future directions. A report of the International Immuno-Oncology Biomarker Working Group on Breast Cancer

DB Page, G Broeckx, CA Jahangir, S Verbandt, RR Gupta, J Thagaard, R Khiroya, Z Kos, K Abduljabbar, G Acosta Haab, B Acs, G Akturk, JS Almeida, I Alvarado-Cabrero, F Azmoudeh-Ardalan, S Badve, NB Baharun, ER Bellolio, V Bheemaraju, KRM Blenman

2023-08-01

Modern histologic imaging platforms coupled with machine learning methods have provided new opportunities to map the spatial distr..

Intratumoral CD8 T cells with a tissue-resident memory phenotype mediate local immunity and immune checkpoint responses in breast cancer

B Virassamy, F Caramia, P Savas, S Sant, J Wang, SN Christo, A Byrne, K Clarke, E Brown, ZL Teo, B von Scheidt, D Freestone, LC Gandolfo, K Weber, J Teply-Szymanski, R Li, SJ Luen, C Denkert, S Loibl, O Lucas

2023-03-13

CD8⁺ tumor-infiltrating lymphocytes with a tissue-resident memory T (T<inf>RM</inf>) cell phenotype are associated with..

Metastatic breast cancer: Til it is too late

P Savas, S Loi

2020-02-01

Paired analysis of primary and metastatic triple-negative breast cancers shows that metastatic disease is an immunodepleted state...